A position is available at the Telethon Institute of Genetics and Medicine (TIGEM) in Pozzuoli, Naples in a project aimed at the study of mitochondrial mediated neurodegeneration in rare mithocondrial disorders and more common conditions.
The position is offered to highly motivated scientist with expertise in cell and molecular biology. Previous laboratory experience with animal models and mouse phenotyping is desirable, but not strictly required.
Starting dates April 2017. Deadline for application open until filled
Interested candidates are requested to send a motivation letter, a CV and emails of 2 references to:
• Dr. Brunella Franco
Prof Medical Genetics, Federico II University of Naples
Principal Investigator, Telethon Institute of Genetics and Medicine (TIGEM)
Pozzuoli, Naples, Italy
Web site www.tigem.it/research/faculty/franco
Representative Lab publications are listed below:
Indrieri A, Grimaldi C, Zucchelli S, Tammaro R, Gustincich S, Franco B (2016).
Synthetic long non-coding RNAs [SINEUPs] rescue defective gene expression in vivo.
Nature Sci Rep. 6:27315.
Liu YP, Tsai IC, Morleo, M, Oh EC, Leitch CC, Massa F, Lee BH, Parker DS, Finley D, Zaghloul NA, Franco B+, Katsanis N+ (2014).
Ciliopathy proteins regulate paracrine signaling by modulating proteasomal degradation of mediators.
J Clin Invest. 124(5):2059-7. +Corresponding authors
Amato R, Morleo M, Giaquinto L, di Bernardo D, Franco B (2014).
A network-based approach to dissect the cilia/centrosome complex interactome.
BMC Genomics. 7;15:658.
Indrieri A, Conte I, Chesi G, Romano A, Quartararo J, Tatè R, Ghezzi D, Zeviani M, Goffrini P, Ferrero I, Bovolenta P, Franco B (2013).
The impairment of HCCS leads to MLS syndrome by activating a non-canonical cell death pathway in the brain and eyes.
EMBO Mol Med. 5(2): 280-93.
Indrieri A, van Rahden VA, Tiranti V, Morleo M, Iaconis D, Tammaro R, D'Amato I, Conte I, Maystadt I, Demuth S, Zvulunov A, Kutsche K, Zeviani M, Franco B (2012).
Mutations in COX7B cause microphthalmia with linear skin lesions, an unconventional mitochondrial disease.
Am J Hum Genet. 91(5): 942-9.
Ferrante MI, Zullo A, Barra A, Bimonte S, Messaddeq N, Studer M, Dolle P, Franco B (2006).
Oral-facial-digital type I protein is required for primary cilia formation and left-right axis specification.
Nat Genet. 38:112-117.