Offerte di Lavoro

The Institute for Genetics at the Faculty of Mathematics and Natural Sciences of the University of Cologne invites applications for the position of a tenured appointment as Professor (W3) in Genetics

We seek individuals with internationally recognized research accomplishments in areas related to genetics and molecular cell biology and a successful track record of external funding. The successful candidate is expected to further strengthen the life science research programs in Cologne, with particular relevance to the Cologne Excellence Cluster on Cellular Stress Responses in Aging Associated Diseases (CECAD) and the local collaborative research centers (SFBs). Furthermore, the successful candidate is expected to engage in the Bachelor's and Master's teaching programmes of the Department of Biology.

At AstraZeneca we work together across global boundaries to make an impact and find answers to challenges. We do this with the upmost integrity even in the most difficult situations because we are committed to doing the right thing. We continuously forge partnerships that help pursue world-class medicines in new ways, combining our people's exceptional skills with those of people from all over the globe.

As a Senior Research Scientist, in Cellular Assay Development or Mechanistic Biology & Profiling in Cambridge, UK, you'll play a pivotal role in channelling our scientific capabilities to make a positive impact on changing patients' lives. IMED (Innovative Medicines and Early Development) focuses on scientific advances in small molecules, oligonucleotides and other emerging technologies and drug discovery platforms across our focus areas.

Il progetto CORBEL lancia un secondo bando attraverso il quale dieci infrastrutture di ricerca dedicate alle scienze mediche e biologiche offrono le loro tecnologie e competenze scientifiche a sostegno di progetti di ricerca avanzata.

Ai candidati vincitori sarà offerto l'accesso alle tecnologie e servizi disponibili presso 10 infrastrutture di ricerca europee per un totale di oltre 90 servizi specialistici, raggruppati in 5 Access Tracks:
- Genotype-to-Phenotype analysis
- Predictive systems pharmacology for safer drugs and chemical products
- Structure-function analysis of large protein complexes
- Marine Metazoan Developmental Models
- Complex multimodal biomarker profiling

Sono aperte alcune posizioni per il Dottorato di Ricerca presso la Scuola Superiore Sant'Anna di Pisa.
Sono disponibili i corsi di Dottorato in Agrobioscienze e Agrobiodiversità i cui dettagli si possono trovare presso http://www.santannapisa.it/it/phd-info.
Per maggiori informazioni sul bando di concorso è possibile contattare: Questo indirizzo email è protetto dagli spambots. E' necessario abilitare JavaScript per vederlo.
Per la discussione di possibili tematiche presso il PlantLab (http://www.santannapisa.it/it/istituto/scienze-della-vita/plant-lab) contattare Chiara Pucciariello ( Questo indirizzo email è protetto dagli spambots. E' necessario abilitare JavaScript per vederlo. ), Francesco Licausi ( Questo indirizzo email è protetto dagli spambots. E' necessario abilitare JavaScript per vederlo. ), Pierdomenico Perata ( Questo indirizzo email è protetto dagli spambots. E' necessario abilitare JavaScript per vederlo. ).

Exploring the regulation of the COP9signalosome/NEDD8 axis by oxidative stress

Increased oxygen-derived reactive species (ROS) levels induce progressive damage to macromolecules, cells, and tissues, eventually leading to diseases such as cancer, inflammation, neurodegeneration, and cardiovascular disorders. Most aerobic organisms sense increased ROS concentrations and respond to protect cellular redox homeostasis through a defense mechanism, including transcriptional modulation and activation of ROS scavengers.

Our lab interest is to determine the effect of elevated ROS levels on cullin NEDDylation and deNEDDylation enzymes and to investigate the ROS defense mechanism underlying the accumulated free NEDD8.

E' disponibile una posizione aperta per un neolaureato in Biologia, Biotecnologie, Biologia Cellulare e dello sviluppo e Genetica e Biologia molecolare, presso il Laboratorio di Virologia e Oncologia molecolare della Fondazione Francesco Balsano.
La Fondazione ha una convenzione sia con la Sapienza Università di Roma che con l'Università di Tor Vergata.

Il neolaureato dovrà effettuare un periodo di prova di almeno 2 mesi con possibilità di partecipare a un Dottorato di Ricerca.

We are currently inviting applications from enthusiastic and independent post-doctoral candidates to join the project:

Role and function of the Fra-1/AP-1 oncogenic transcription factor in metastatic breast cancer

Project: The Fra-1 protein is a component of the ubiquitous family of AP- 1/(Fos-Jun) transcriptional complexes, which exerts major roles in physiology and pathology. It is abnormally overexpressed in hyperphosphorylated forms in the so-called Triple Negative Breast Cancers (TNBCs), where it plays a key role in aggressiveness and metastasis.

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