Postdoctoral positions are available for highly motivated Ph.D. and/or M.D. to work on host cell reprogramming by human tumor viruses. We study the mechanisms by which oncogenic herpesviruses interfere with cellular functions regulated by ubiquitin and ubiquitin-like post-translational modifications and the role of virus-induced DNA damage and genomic instability in oncogenesis.
For examples of recent publications on the subject see: Gastaldello et al. Nature Cell Biol. 2010, 12:351-61; Kamranvar & Masucci Luekemia 2011, 25:1017-25; Gastaldello et al. J Mol Cell Biol. 2012 4:242-51; Coppotelli et al. Nucleic Acids Res. 2013, 41:2950-62. Gastaldello et al. PLoSPathog 2013 9(10):e1003664; Chen et al. Oncogene. 2016 doi: 10.1038/onc.2015.450; Li et al. PLoS Pathog. 2017 Apr 17;13(4):e1006338.
Candidates with a PhD in Molecular and Cell Biology or Molecular Virology obtained during the past four years and with experience in the fields of molecular biology, protein chemistry or DNA damage responses are encouraged to apply. Salary will be negotiated depending on competence according to the guidelines of the Karolinska Institutet.