A Parkinson's UK-funded position is available in the laboratory of Dr Heike Laman at the University of Cambridge in the Department of Pathology.
We are seeking a highly motivated and talented post-doctoral research scientist to investigate the Parkinson's disease-associated E3 ubiquitin ligase Fbxo7/PARK15 and its role in neurodegeneration. The goal of this project is to investigate Fbxo7-regulated pathways and how their mis-regulation causes neuronal loss in the midbrain. To tackle these questions, a wide range of techniques will be used, including biochemical and cellular assays, stem cell technologies and in vivo modelling. Productive experience in at least one of the following areas would be highly advantageous: mitochondrial biology, mouse models of neurodegeneration, and ubiquitin biology.
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