Post-doctoral Research Scientist presso il lab di Benoit PALANCADE @ Institut Jacques Monod, Paris, France

  • 25 Sep 2018

We are looking for a highly-motivated Post-doctoral Research Scientist with knowledge in the fields of gene expression and/or genetic stability to join the team « RNA biogenesis and genome homeostasis » led by Benoit PALANCADE at Institut Jacques Monod (CNRS/Université Paris Diderot, Paris, France – http://www.ijm.fr).

Current work in the lab aims to uncover novel regulations targeting mRNA metabolism and to decipher their impact on gene expression patterns and genomic integrity. We are specially interested in understanding which cis- and trans-acting factors influence the formation of genotoxic DNA:RNA hybrids, and thereby challenge genome dynamics and stability. The post-doctoral fellow will more particularly focus on the functional characterization of novel factors restricting hybrid-dependent genetic instability, which we previously uncovered through innovative screens in budding yeast. For this purpose, the project will combine genome-wide approaches with mechanistic studies based on yeast genetics and molecular biology/biochemical assays. The post-doctoral fellow will have access to the leading-edge core facilities available within the IJM building, and will benefit from a highly dynamic scientific environment.

Qualifications
You will have a PhD in biological or biochemical sciences and demonstrable experience in genetics and molecular biology techniques. Previous experience in yeast biology or bioinformatic analyses of genomic data will be appreciated but is not essential. You will need strong organizational and team working abilities to take projects from conception to completion, as well as verbal and written communication skills in English (French is not mandatory). You will have a CV and publication record that would be competitive for national/international post-doctoral fellowships.

Application details
The position is funded by ANR (Agence Nationale de la Recherche), and is fixed term for up to 2 years with the eventuality of an extension. The position can start at any time after November 1st 2018.
Applications including a CV and a cover letter summarizing current and future research interests, as well as the contact details of 2 referees, should be ultimately submitted through the Emploi CNRS portal (http://bit.ly/2Mg0ZrO), but preliminary inquiries and additional informations can be discussed by e-mail to benoit.palancade@ijm.fr.

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